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Seralini svarar fyrir sig

Landvernd    26.9.2012
Landvernd
Answer to "Expert reaction..." (on www.sciencemediacenter.org) Gilles-Eric Seralini, Ph.D., co-director of the Unit on multidisciplinary Risks, Quality and Sustainable Environment (MRSH-CNRS), University of Caen and Joël Spiroux de Vendômois, M.D specialist on environmental pathologies, CRIIGEN president (www.criigen.org). Members of ENSSER (ensser.org). First of all we have published the most comprehensive life long mammalian toxicological study ever performed on an agricultural GMO and a pesticide in formulation with its adjuvants, because we are exposed daily to these products. Overall for NK603 no study was over 90 days, for the authorizations Monsanto worked on 10 rats measured per group on Sprague Dawley rats (blood, urine analyses...). If 10 rats is a too small number per group to conclude on safety, like W.H. says, then the NK603 and most agricultural GMOs should be forbidden. We are surprised for that by the violent and rapid answers by scientists within 24 h? What are their financial interest?, or were they involved in the insufficient assessment of agricultural GMOs on health as we have published (papers joined). We are not surprised that the first reactions come essentially from people that do not have published any peer reviewed scientific papers on mammalian or human pathophysiological and toxicological studies. This is the case for Maurice Moloney working on GMO development and patents, not on food security. David Spiegelhalter is a statistician defending GMOs. Wendy Harwood works on the techniques of transgenesis at a research level to promote genetic constructions. Anthony Trewavas is one of the most known pro-GMO activists and has a list of scientific papers not on the subject but is known to attack organic agriculture. Ottoline Leyser has never worked on animals but on plants, like Mark Tester on grains technology. Tom Sanders has effectively nutrition but not really toxicological papers but never on GMOs. Alan Boobis by contrast, probably the coordinator, has publications in the field but is well known for his links with Monsanto, Bayer, Basf, etc., companies developing GMOs. All this may explain the arguments that do not recognize the length and detailed study but rather focus so immediately on three kinds of arguments: I. Non serious or stupid ones: (i) The Fig. 1 or others do not present any control according to M.M. They are in fact represented in dotted lines like indicated in the legend. This written criticism is unacceptable from a real scientist knowing how to read a legend. W.H. says the same. The controls in Table (2) are always the same numbers than the treated groups (10) by contrast to M.M. affirmation. The numbers of rats in parentheses in Table 2 are the ones reached by pathologies by the end of the experiment as indicated in the legend. Again, this is a lack of knowledge in reading. This is unacceptable at this level. For sure, this may be explained by the fact that M.M. has no publications in this domain. The photographs of organs and tissues include of course controls (Fig. 3) indicated by C. The photograph of a normal rat of course is useless even if we understand that M.M. has never worked on rats. There were 3 tumors in controls up to 650 days, 2 times more in 7 treated groups on 9, for instance. These are crude results by contrast to the "superficial" D.S. report. (ii) The intermediate dosing has been performed (answer to M.M.). Three doses have been given for each treatment as recommended by OECD norms, by contrast to what has been performed (2 doses only) by Monsanto in the regulatory tests given for NK603 authorization (like for their other GMOs, Hammond et al., 2004). However with 2 measures they were already claiming no dose-response relationship! The full data that have served to authorize NK603 and Roundup formulations should be made available too, in order to answer to W.H. Civil society is now requesting that by law. Then it will be possible to compare. (iii) Apparently W.H. does not know the Hammond study that has allowed the GM maize authorization. It contained in the treated groups 11 or 33% maize. The diet does not contain 11% maize but 11% GM maize on 33% maize. Is W.H. a specialist in rat nutrition? (iv) Erroneous, false or stupid affirmations in the list of further comments: No results given for non GM maize, no problems reported, there are no 2-year long regulatory tests in UK, the authors do not suggest effects of GM (O.L.), no epidemiological studies demonstrated risks in countries where there is no GM traceability, (of course! M.T.), longevity increases in the US: NO...). The "historical" ?? or no maize based diets should be included. Too many questions in the same protocol if this is done, this would artificially increase the variability of the control group, like Monsanto did in 90 days tests (answer to A.B.). Wrong : The pesticide itself has been subject to long term studies in rodents... A.B. speaks about glyphosate ignoring the difference with Roundup, we guess. II. The ones that can be discussed:

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